Optimization of Culture Conditions for Production of the Anti-Leukemic Glutaminase Free L-Asparaginase by Newly Isolated Streptomyces olivaceus NEAE-119 Using Response Surface Methodology

Among the antitumor drugs, bacterial enzyme L-asparaginase has been employed as the most effective chemotherapeutic agent in pediatric oncotherapy especially for acute lymphoblastic leukemia. Glutaminase free L-asparaginase producing actinomycetes were isolated from soil samples collected from Egypt...

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Detalles Bibliográficos
Autores principales: El-Naggar, Noura El-Ahmady, Moawad, Hassan, El-Shweihy, Nancy M., El-Ewasy, Sara M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477217/
https://www.ncbi.nlm.nih.gov/pubmed/26180806
http://dx.doi.org/10.1155/2015/627031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477217/
https://www.ncbi.nlm.nih.gov/pubmed/26180806
http://dx.doi.org/10.1155/2015/627031

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