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In vivo imaging of endogenous enzyme activities using luminescent 1,2-dioxetane compounds

BACKGROUND: Here we present a non-invasive imaging method for visualizing endogenous enzyme activities in living animals. This optical imaging method is based on an energy transfer principle termed chemically initiated electron exchange luminescence (CIEEL). The light energy is provided by enzymatic...

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Detalles Bibliográficos
Autores principales: Tseng, Jen-Chieh, Kung, Andrew L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477311/
https://www.ncbi.nlm.nih.gov/pubmed/26100615
http://dx.doi.org/10.1186/s12929-015-0155-x