The Basic Helix-Loop-Helix Transcription Factor NEUROG3 Is Required for Development of the Human Endocrine Pancreas

Neurogenin3 (NEUROG3) is a basic helix-loop-helix transcription factor required for development of the endocrine pancreas in mice. In contrast, humans with NEUROG3 mutations are born with endocrine pancreas function, calling into question whether NEUROG3 is required for human endocrine pancreas deve...

Descripción completa

Detalles Bibliográficos
Autores principales: McGrath, Patrick S., Watson, Carey L., Ingram, Cameron, Helmrath, Michael A., Wells, James M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2015
Materias:
Islet Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477351/
https://www.ncbi.nlm.nih.gov/pubmed/25650326
http://dx.doi.org/10.2337/db14-1412

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477351/
https://www.ncbi.nlm.nih.gov/pubmed/25650326
http://dx.doi.org/10.2337/db14-1412

Ejemplares similares