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The Basic Helix-Loop-Helix Transcription Factor NEUROG3 Is Required for Development of the Human Endocrine Pancreas
Neurogenin3 (NEUROG3) is a basic helix-loop-helix transcription factor required for development of the endocrine pancreas in mice. In contrast, humans with NEUROG3 mutations are born with endocrine pancreas function, calling into question whether NEUROG3 is required for human endocrine pancreas deve...
Autores principales: | McGrath, Patrick S., Watson, Carey L., Ingram, Cameron, Helmrath, Michael A., Wells, James M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477351/ https://www.ncbi.nlm.nih.gov/pubmed/25650326 http://dx.doi.org/10.2337/db14-1412 |
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