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Orthologous endogenous retroviruses exhibit directional selection since the chimp-human split

BACKGROUND: Endogenous retroviruses (ERVs) are often viewed as selfish DNA that do not contribute to host phenotype. Yet ERVs have also been co-opted to play important roles in the maintenance of stem cell identity and placentation, amongst other things. This has led to debate over whether the typic...

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Detalles Bibliográficos
Autores principales: Gemmell, Patrick, Hein, Jotun, Katzourakis, Aris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477479/
https://www.ncbi.nlm.nih.gov/pubmed/26088204
http://dx.doi.org/10.1186/s12977-015-0172-6