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N-terminal functional domain of Gasdermin A3 regulates mitochondrial homeostasis via mitochondrial targeting

BACKGROUND: The epidermis forms a critical barrier that is maintained by orchestrated programs of proliferation, differentiation, and cell death. Gene mutations that disturb this turnover process may cause skin diseases. Human GASDERMIN A (GSDMA) is frequently silenced in gastric cancer cell lines a...

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Detalles Bibliográficos
Autores principales: Lin, Pei-Hsuan, Lin, Hsien-Yi, Kuo, Cheng-Chin, Yang, Liang-Tung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477613/
https://www.ncbi.nlm.nih.gov/pubmed/26100518
http://dx.doi.org/10.1186/s12929-015-0152-0