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Intermolecular ‘cross-torque’: the N(4)-cytosine propargyl residue is rotated to the ‘CH’-edge as a result of Watson–Crick interaction

Propargyl groups are attractive functional groups for labeling purposes, as they allow CuAAC-mediated bioconjugation. Their size minimally exceeds that of a methyl group, the latter being frequent in natural nucleotide modifications. To understand under which circumstances propargyl-containing oligo...

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Detalles Bibliográficos
Autores principales: Domingo, Olwen, Hellmuth, Isabell, Jäschke, Andres, Kreutz, Christoph, Helm, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477647/
https://www.ncbi.nlm.nih.gov/pubmed/25934805
http://dx.doi.org/10.1093/nar/gkv285