HAT3-mediated acetylation of PCNA precedes PCNA monoubiquitination following exposure to UV radiation in Leishmania donovani

Histone modifications impact various processes. In examining histone acetyltranferase HAT3 of Leishmania donovani, we find elimination of HAT3 causes decreased cell viability due to defects in histone deposition, and aberrant cell cycle progression pattern. HAT3 associates with proliferating cell nu...

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Detalles Bibliográficos
Autores principales: Kumar, Devanand, Saha, Swati
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477661/
https://www.ncbi.nlm.nih.gov/pubmed/25948582
http://dx.doi.org/10.1093/nar/gkv431

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477661/
https://www.ncbi.nlm.nih.gov/pubmed/25948582
http://dx.doi.org/10.1093/nar/gkv431

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