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Shape-selective recognition of DNA abasic sites by metallohelices: inhibition of human AP endonuclease 1
Loss of a base in DNA leading to creation of an abasic (AP) site leaving a deoxyribose residue in the strand, is a frequent lesion that may occur spontaneously or under the action of various physical and chemical agents. Progress in the understanding of the chemistry and enzymology of abasic DNA lar...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477665/ https://www.ncbi.nlm.nih.gov/pubmed/25940617 http://dx.doi.org/10.1093/nar/gkv438 |