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Shape-selective recognition of DNA abasic sites by metallohelices: inhibition of human AP endonuclease 1

Loss of a base in DNA leading to creation of an abasic (AP) site leaving a deoxyribose residue in the strand, is a frequent lesion that may occur spontaneously or under the action of various physical and chemical agents. Progress in the understanding of the chemistry and enzymology of abasic DNA lar...

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Detalles Bibliográficos
Autores principales: Malina, Jaroslav, Scott, Peter, Brabec, Viktor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477665/
https://www.ncbi.nlm.nih.gov/pubmed/25940617
http://dx.doi.org/10.1093/nar/gkv438