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Prediction of nucleic acid binding probability in proteins: a neighboring residue network based score

We describe a general binding score for predicting the nucleic acid binding probability in proteins. The score is directly derived from physicochemical and evolutionary features and integrates a residue neighboring network approach. Our process achieves stable and high accuracies on both DNA- and RN...

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Detalles Bibliográficos
Autores principales: Miao, Zhichao, Westhof, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477668/
https://www.ncbi.nlm.nih.gov/pubmed/25940624
http://dx.doi.org/10.1093/nar/gkv446