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Human RNase P ribonucleoprotein is required for formation of initiation complexes of RNA polymerase III

Human RNase P is implicated in transcription of small non-coding RNA genes by RNA polymerase III (Pol III), but the precise role of this ribonucleoprotein therein remains unknown. We here show that targeted destruction of HeLa nuclear RNase P inhibits transcription of 5S rRNA genes in whole cell ext...

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Detalles Bibliográficos
Autores principales: Serruya, Raphael, Orlovetskie, Natalie, Reiner, Robert, Dehtiar-Zilber, Yana, Wesolowski, Donna, Altman, Sidney, Jarrous, Nayef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477669/
https://www.ncbi.nlm.nih.gov/pubmed/25953854
http://dx.doi.org/10.1093/nar/gkv447