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Assembly constraints drive co-evolution among ribosomal constituents

Ribosome biogenesis, a central and essential cellular process, occurs through sequential association and mutual co-folding of protein–RNA constituents in a well-defined assembly pathway. Here, we construct a network of co-evolving nucleotide/amino acid residues within the ribosome and demonstrate th...

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Detalles Bibliográficos
Autores principales: Mallik, Saurav, Akashi, Hiroshi, Kundu, Sudip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477670/
https://www.ncbi.nlm.nih.gov/pubmed/25956649
http://dx.doi.org/10.1093/nar/gkv448