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The identity of the discriminator base has an impact on CCA addition

CCA-adding enzymes synthesize and maintain the C-C-A sequence at the tRNA 3′-end, generating the attachment site for amino acids. While tRNAs are the most prominent substrates for this polymerase, CCA additions on non-tRNA transcripts are described as well. To identify general features for substrate...

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Detalles Bibliográficos
Autores principales: Wende, Sandra, Bonin, Sonja, Götze, Oskar, Betat, Heike, Mörl, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477674/
https://www.ncbi.nlm.nih.gov/pubmed/25958396
http://dx.doi.org/10.1093/nar/gkv471