XPD localizes in mitochondria and protects the mitochondrial genome from oxidative DNA damage

Xeroderma pigmentosum group D (XPD/ERCC2) encodes an ATP-dependent helicase that plays essential roles in both transcription and nucleotide excision repair of nuclear DNA, however, whether or not XPD exerts similar functions in mitochondria remains elusive. In this study, we provide the first eviden...

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Detalles Bibliográficos
Autores principales: Liu, Jing, Fang, Hongbo, Chi, Zhenfen, Wu, Zan, Wei, Di, Mo, Dongliang, Niu, Kaifeng, Balajee, Adayabalam S., Hei, Tom K., Nie, Linghu, Zhao, Yongliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477675/
https://www.ncbi.nlm.nih.gov/pubmed/25969448
http://dx.doi.org/10.1093/nar/gkv472

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477675/
https://www.ncbi.nlm.nih.gov/pubmed/25969448
http://dx.doi.org/10.1093/nar/gkv472

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