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Global gene expression changes in liver following hepatocyte nuclear factor 4 alpha deletion in adult mice

Hepatocyte nuclear factor 4 alpha (HNF4α) is known as the master regulator of hepatic differentiation, which regulates over 60% of the hepatocyte specific genes. Recent studies including this (Walesky et al. Am J Physiol Gastrointest Liver Physiol. 304:G26-37, 2013) demonstrated that HNF4α also inhi...

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Detalles Bibliográficos
Autores principales: Gunewardena, Sumedha, Walesky, Chad, Apte, Udayan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477707/
https://www.ncbi.nlm.nih.gov/pubmed/26120557
http://dx.doi.org/10.1016/j.gdata.2015.05.037