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NKCC1 and NKCC2: The pathogenetic role of cation-chloride cotransporters in hypertension

This review summarizes the data on the functional significance of ubiquitous (NKCC1) and renal-specific (NKCC2) isoforms of electroneutral sodium, potassium and chloride cotransporters. These carriers contribute to the pathogenesis of hypertension via regulation of intracellular chloride concentrati...

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Detalles Bibliográficos
Autores principales: Orlov, Sergei N., Koltsova, Svetlana V., Kapilevich, Leonid V., Gusakova, Svetlana V., Dulin, Nickolai O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477834/
https://www.ncbi.nlm.nih.gov/pubmed/26114157
http://dx.doi.org/10.1016/j.gendis.2015.02.007