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NKCC1 and NKCC2: The pathogenetic role of cation-chloride cotransporters in hypertension
This review summarizes the data on the functional significance of ubiquitous (NKCC1) and renal-specific (NKCC2) isoforms of electroneutral sodium, potassium and chloride cotransporters. These carriers contribute to the pathogenesis of hypertension via regulation of intracellular chloride concentrati...
Autores principales: | Orlov, Sergei N., Koltsova, Svetlana V., Kapilevich, Leonid V., Gusakova, Svetlana V., Dulin, Nickolai O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Chongqing Medical University
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477834/ https://www.ncbi.nlm.nih.gov/pubmed/26114157 http://dx.doi.org/10.1016/j.gendis.2015.02.007 |
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