Binding of STIL to Plk4 activates kinase activity to promote centriole assembly

Centriole duplication occurs once per cell cycle in order to maintain control of centrosome number and ensure genome integrity. Polo-like kinase 4 (Plk4) is a master regulator of centriole biogenesis, but how its activity is regulated to control centriole assembly is unclear. Here we used gene editi...

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Detalles Bibliográficos
Autores principales: Moyer, Tyler C., Clutario, Kevin M., Lambrus, Bramwell G., Daggubati, Vikas, Holland, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477857/
https://www.ncbi.nlm.nih.gov/pubmed/26101219
http://dx.doi.org/10.1083/jcb.201502088

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477857/
https://www.ncbi.nlm.nih.gov/pubmed/26101219
http://dx.doi.org/10.1083/jcb.201502088

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