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A cell-free CENP-A assembly system defines the chromatin requirements for centromere maintenance

Centromeres are defined by the presence of CENP-A nucleosomes in chromatin and are essential for accurate chromosome segregation. Centromeric chromatin epigenetically seeds new CENP-A nucleosome formation, thereby maintaining functional centromeres as cells divide. The features within centromeric ch...

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Detalles Bibliográficos
Autores principales: Westhorpe, Frederick G., Fuller, Colin J., Straight, Aaron F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477859/
https://www.ncbi.nlm.nih.gov/pubmed/26076692
http://dx.doi.org/10.1083/jcb.201503132