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A cell-free CENP-A assembly system defines the chromatin requirements for centromere maintenance
Centromeres are defined by the presence of CENP-A nucleosomes in chromatin and are essential for accurate chromosome segregation. Centromeric chromatin epigenetically seeds new CENP-A nucleosome formation, thereby maintaining functional centromeres as cells divide. The features within centromeric ch...
Autores principales: | Westhorpe, Frederick G., Fuller, Colin J., Straight, Aaron F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477859/ https://www.ncbi.nlm.nih.gov/pubmed/26076692 http://dx.doi.org/10.1083/jcb.201503132 |
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