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Calcium release through P2X4 activates calmodulin to promote endolysosomal membrane fusion

Intra-endolysosomal Ca(2+) release is required for endolysosomal membrane fusion with intracellular organelles. However, the molecular mechanisms for intra-endolysosomal Ca(2+) release and the downstream Ca(2+) targets involved in the fusion remain elusive. Previously, we demonstrated that endolysos...

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Detalles Bibliográficos
Autores principales: Cao, Qi, Zhong, Xi Zoë, Zou, Yuanjie, Murrell-Lagnado, Ruth, Zhu, Michael X., Dong, Xian-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477861/
https://www.ncbi.nlm.nih.gov/pubmed/26101220
http://dx.doi.org/10.1083/jcb.201409071