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Centromere protein F includes two sites that couple efficiently to depolymerizing microtubules

Firm attachments between kinetochores and dynamic spindle microtubules (MTs) are important for accurate chromosome segregation. Centromere protein F (CENP-F) has been shown to include two MT-binding domains, so it may participate in this key mitotic process. Here, we show that the N-terminal MT-bind...

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Detalles Bibliográficos
Autores principales: Volkov, Vladimir A., Grissom, Paula M., Arzhanik, Vladimir K., Zaytsev, Anatoly V., Renganathan, Kutralanathan, McClure-Begley, Tristan, Old, William M., Ahn, Natalie, McIntosh, J. Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477864/
https://www.ncbi.nlm.nih.gov/pubmed/26101217
http://dx.doi.org/10.1083/jcb.201408083