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Increasing inflationary T-cell responses following transient depletion of MCMV-specific memory T cells

Murine CMV (MCMV) infection induces effector CD8(+) T cells that continue to increase in frequency after acute infection (“inflation”) and are stably maintained at a high frequency, with up to 20% of the CD8(+) T-cell compartment being specific for one epitope, although the flexibility and turnover...

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Detalles Bibliográficos
Autores principales: Sims, Stuart, Klenerman, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477908/
https://www.ncbi.nlm.nih.gov/pubmed/25331015
http://dx.doi.org/10.1002/eji.201445016