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Prevalence and Clinicopathological Characteristics of HER2 and BRAF Mutation in Chinese Patients with Lung Adenocarcinoma

AIMS: To determine the prevalence and clinicopathological characteristics of BRAF V600E mutation and HER2 exon 20 insertions in Chinese lung adenocarcinoma (ADC) patients. METHODS: Given the fact that the driver mutations are mutually exclusive in lung ADCs, 204 EGFR/KRAS wild-type cases were enroll...

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Detalles Bibliográficos
Autores principales: Shan, Ling, Qiu, Tian, Ling, Yun, Guo, Lei, Zheng, Bo, Wang, Bingning, Li, Wenbin, Li, Lin, Ying, Jianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477932/
https://www.ncbi.nlm.nih.gov/pubmed/26102513
http://dx.doi.org/10.1371/journal.pone.0130447