Translational Upregulation of an Individual p21(Cip1) Transcript Variant by GCN2 Regulates Cell Proliferation and Survival under Nutrient Stress

Multiple transcripts encode for the cell cycle inhibitor p21(Cip1). These transcripts produce identical proteins but differ in their 5’ untranslated regions (UTRs). Although several stresses that induce p21 have been characterized, the mechanisms regulating the individual transcript variants and the...

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Detalles Bibliográficos
Autores principales: Lehman, Stacey L., Cerniglia, George J., Johannes, Gregg J., Ye, Jiangbin, Ryeom, Sandra, Koumenis, Constantinos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477940/
https://www.ncbi.nlm.nih.gov/pubmed/26102367
http://dx.doi.org/10.1371/journal.pgen.1005212

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477940/
https://www.ncbi.nlm.nih.gov/pubmed/26102367
http://dx.doi.org/10.1371/journal.pgen.1005212

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