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Secreted Phosphoprotein 1 Promoter Genetic Variants Are Associated with the Response to Pegylated Interferon α Plus Ribavirin Combination Therapy in Egyptian Patients with Chronic Hepatitis C Virus Infection

BACKGROUND/AIMS: The T-helper 1 (TH1) immune reaction is essential for the eradication of hepatitis C virus (HCV) during pegylated interferon α (PEG-IFN-α)- and ribavirin (RBV)-based therapy in chronic HCV patients. Secreted phosphoprotein 1 (SPP1) was shown to be a crucial cytokine for the initiati...

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Detalles Bibliográficos
Autores principales: Ali, Fahmy T., Ali, Mohamed A. M., Elgizawy, Mayada M. A., Elsawy, Ahmed M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Gut and Liver 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477996/
https://www.ncbi.nlm.nih.gov/pubmed/25717047
http://dx.doi.org/10.5009/gnl14162