Regulation of Insulin Receptor Trafficking by Bardet Biedl Syndrome Proteins

Insulin and its receptor are critical for the regulation of metabolic functions, but the mechanisms underlying insulin receptor (IR) trafficking to the plasma membrane are not well understood. Here, we show that Bardet Biedl Syndrome (BBS) proteins are necessary for IR localization to the cell surfa...

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Detalles Bibliográficos
Autores principales: Starks, Rachel D., Beyer, Andreas M., Guo, Deng Fu, Boland, Lauren, Zhang, Qihong, Sheffield, Val C., Rahmouni, Kamal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4478011/
https://www.ncbi.nlm.nih.gov/pubmed/26103456
http://dx.doi.org/10.1371/journal.pgen.1005311

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4478011/
https://www.ncbi.nlm.nih.gov/pubmed/26103456
http://dx.doi.org/10.1371/journal.pgen.1005311

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