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Integrative Transcriptome Profiling of Cognitive Aging and Its Preservation through Ser/Thr Protein Phosphatase Regulation

Environmental enrichment has been reported to delay or restore age-related cognitive deficits, however, a mechanism to account for the cause and progression of normal cognitive decline and its preservation by environmental enrichment is lacking. Using genome-wide SAGE-Seq, we provide a global assess...

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Detalles Bibliográficos
Autores principales: Park, C. Sehwan, Valomon, Amandine, Welzl, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4478024/
https://www.ncbi.nlm.nih.gov/pubmed/26102285
http://dx.doi.org/10.1371/journal.pone.0130891