Elongation Factor 1A-1 Is a Mediator of Hepatocyte Lipotoxicity Partly through Its Canonical Function in Protein Synthesis

Elongation factor 1A-1 (eEF1A-1) has non-canonical functions in regulation of the actin cytoskeleton and apoptosis. It was previously identified through a promoter-trap screen as a mediator of fatty acid-induced cell death (lipotoxicity), and was found to participate in this process downstream of ER...

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Detalles Bibliográficos
Autores principales: Stoianov, Alexandra M., Robson, Debra L., Hetherington, Alexandra M., Sawyez, Cynthia G., Borradaile, Nica M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4478042/
https://www.ncbi.nlm.nih.gov/pubmed/26102086
http://dx.doi.org/10.1371/journal.pone.0131269

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4478042/
https://www.ncbi.nlm.nih.gov/pubmed/26102086
http://dx.doi.org/10.1371/journal.pone.0131269

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