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Neural Stem Cells in the Adult Subventricular Zone Oxidize Fatty Acids to Produce Energy and Support Neurogenic Activity

Neural activity is tightly coupled to energy consumption, particularly sugars such as glucose. However, we find that, unlike mature neurons and astrocytes, neural stem/progenitor cells (NSPCs) do not require glucose to sustain aerobic respiration. NSPCs within the adult subventricular zone (SVZ) exp...

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Detalles Bibliográficos
Autores principales: Stoll, Elizabeth A., Makin, Rebecca, Sweet, Ian R., Trevelyan, Andrew J., Miwa, Satomi, Horner, Philip J., Turnbull, Douglass M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4478223/
https://www.ncbi.nlm.nih.gov/pubmed/25919237
http://dx.doi.org/10.1002/stem.2042