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Contribution of two conserved histidines to the dual activity of archaeal RNA guide-dependent and -independent pseudouridine synthase Cbf5

In all organisms, several distinct stand-alone pseudouridine synthase (PUS) family enzymes are expressed to isomerize uridine into pseudouridine (Ψ) by specific recognition of RNAs. In addition, Ψs are generated in Archaea and Eukaryotes by PUS enzymes which are organized as ribonucleoprotein partic...

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Detalles Bibliográficos
Autores principales: Tillault, Anne-Sophie, Fourmann, Jean-Baptiste, Loegler, Christine, Wieden, Hans-Joachim, Kothe, Ute, Charpentier, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4478342/
https://www.ncbi.nlm.nih.gov/pubmed/25990001
http://dx.doi.org/10.1261/rna.051425.115