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Xenopus CAF1 requires NOT1-mediated interaction with 4E-T to repress translation in vivo

RNA-regulatory factors bound to 3′ UTRs control translation and stability. Repression often is associated with poly(A) removal. The deadenylase CAF1 is a core component of the CCR4–NOT complex. Our prior studies established that CAF1 represses translation independent of deadenylation. We sought the...

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Detalles Bibliográficos
Autores principales: Waghray, Shruti, Williams, Clay, Coon, Joshua J., Wickens, Marvin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4478352/
https://www.ncbi.nlm.nih.gov/pubmed/26015597
http://dx.doi.org/10.1261/rna.051565.115