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In situ imaging and proteome profiling indicate andrographolide is a highly promiscuous compound

Natural products represent an enormous source of pharmacologically useful compounds, and are often used as the starting point in modern drug discovery. Many biologically interesting natural products are however not being pursued as potential drug candidates, partly due to a lack of well-defined mech...

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Detalles Bibliográficos
Autores principales: Li, Lin, Wijaya, Hadhi, Samanta, Sanjay, Lam, Yulin, Yao, Shao Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4478469/
https://www.ncbi.nlm.nih.gov/pubmed/26105662
http://dx.doi.org/10.1038/srep11522