Heat stress induced apoptosis is triggered by transcription-independent p53, Ca(2+) dyshomeostasis and the subsequent Bax mitochondrial translocation

In this study, We demonstrated that Bax mitochondrial translocation plays a vital role in the initiation of the mitochondrial signaling pathway upon activation by heat stress. In addition, both p53 mitochondrial translocation and Ca(2+) signal mediated MPTP opening activate Bax mitochondrial translo...

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Detalles Bibliográficos
Autores principales: Gu, Z. T., Li, L., WU, F., Zhao, P., Yang, H., Liu, Y. S., Geng, Y., Zhao, M., Su, L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4478470/
https://www.ncbi.nlm.nih.gov/pubmed/26105784
http://dx.doi.org/10.1038/srep11497

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4478470/
https://www.ncbi.nlm.nih.gov/pubmed/26105784
http://dx.doi.org/10.1038/srep11497

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