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Single-Cell Based Quantitative Assay of Chromosome Transmission Fidelity

Errors in mitosis are a primary cause of chromosome instability (CIN), generating aneuploid progeny cells. Whereas a variety of factors can influence CIN, under most conditions mitotic errors are rare events that have been difficult to measure accurately. Here we report a green fluorescent protein−b...

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Detalles Bibliográficos
Autores principales: Zhu, Jin, Heinecke, Dominic, Mulla, Wahid A., Bradford, William D., Rubinstein, Boris, Box, Andrew, Haug, Jeffrey S., Li, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4478535/
https://www.ncbi.nlm.nih.gov/pubmed/25823586
http://dx.doi.org/10.1534/g3.115.017913