Response of Polygenic Traits Under Stabilizing Selection and Mutation When Loci Have Unequal Effects

We consider an infinitely large population under stabilizing selection and mutation in which the allelic effects determining a polygenic trait vary between loci. We obtain analytical expressions for the stationary genetic variance as a function of the distribution of effects, mutation rate, and sele...

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Detalles Bibliográficos
Autores principales: Jain, Kavita, Stephan, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2015
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4478537/
https://www.ncbi.nlm.nih.gov/pubmed/25834214
http://dx.doi.org/10.1534/g3.115.017970

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4478537/
https://www.ncbi.nlm.nih.gov/pubmed/25834214
http://dx.doi.org/10.1534/g3.115.017970

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