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Response of Polygenic Traits Under Stabilizing Selection and Mutation When Loci Have Unequal Effects
We consider an infinitely large population under stabilizing selection and mutation in which the allelic effects determining a polygenic trait vary between loci. We obtain analytical expressions for the stationary genetic variance as a function of the distribution of effects, mutation rate, and sele...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Genetics Society of America
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4478537/ https://www.ncbi.nlm.nih.gov/pubmed/25834214 http://dx.doi.org/10.1534/g3.115.017970 |