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One-Step Enzymatic Modification of the Cell Surface Redirects Cellular Cytotoxicity and Parasite Tropism

[Image: see text] Surface display of engineered proteins has many useful applications. The expression of a synthetic chimeric antigen receptor composed of an extracellular tumor-specific antibody fragment linked to a cytosolic activating motif in engineered T cells is now considered a viable approac...

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Detalles Bibliográficos
Autores principales: Swee, Lee Kim, Lourido, Sebastian, Bell, George W., Ingram, Jessica R., Ploegh, Hidde L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4478597/
https://www.ncbi.nlm.nih.gov/pubmed/25360987
http://dx.doi.org/10.1021/cb500462t