C8orf4 negatively regulates self-renewal of liver cancer stem cells via suppression of NOTCH2 signalling

Liver cancer stem cells (CSCs) harbour self-renewal and differentiation properties, accounting for chemotherapy resistance and recurrence. However, the molecular mechanisms to sustain liver CSCs remain largely unknown. In this study, based on analysis of several hepatocellular carcinoma (HCC) transc...

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Detalles Bibliográficos
Autores principales: Zhu, Pingping, Wang, Yanying, Du, Ying, He, Lei, Huang, Guanling, Zhang, Geng, Yan, Xinlong, Fan, Zusen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479000/
https://www.ncbi.nlm.nih.gov/pubmed/25985737
http://dx.doi.org/10.1038/ncomms8122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479000/
https://www.ncbi.nlm.nih.gov/pubmed/25985737
http://dx.doi.org/10.1038/ncomms8122

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