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Circular RNA biogenesis can proceed through an exon-containing lariat precursor

Pervasive expression of circular RNA is a recently discovered feature of eukaryotic gene expression programs, yet its function remains largely unknown. The presumed biogenesis of these RNAs involves a non-canonical ‘backsplicing’ event. Recent studies in mammalian cell culture posit that backsplicin...

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Detalles Bibliográficos
Autores principales: Barrett, Steven P, Wang, Peter L, Salzman, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479058/
https://www.ncbi.nlm.nih.gov/pubmed/26057830
http://dx.doi.org/10.7554/eLife.07540