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Proteins interaction network and modeling of IGVH mutational status in chronic lymphocytic leukemia

BACKGROUND: Chronic lymphocytic leukemia (CLL) is an incurable malignancy of mature B-lymphocytes, characterized as being a heterogeneous disease with variable clinical manifestation and survival. Mutational statuses of rearranged immunoglobulin heavy chain variable (IGVH) genes has been consider on...

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Detalles Bibliográficos
Autores principales: Álvarez-Silva, María Camila, Yepes, Sally, Torres, Maria Mercedes, González Barrios, Andrés Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479082/
https://www.ncbi.nlm.nih.gov/pubmed/26088082
http://dx.doi.org/10.1186/s12976-015-0008-z