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Serial expression analysis of breast tumors during neoadjuvant chemotherapy reveals changes in cell cycle and immune pathways associated with recurrence and response

INTRODUCTION: The molecular biology involving neoadjuvant chemotherapy (NAC) response is poorly understood. To elucidate the impact of NAC on the breast cancer transcriptome and its association with clinical outcome, we analyzed gene expression data derived from serial tumor samples of patients with...

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Detalles Bibliográficos
Autores principales: Magbanua, Mark Jesus M., Wolf, Denise M., Yau, Christina, Davis, Sarah E., Crothers, Julia, Au, Alfred, Haqq, Christopher M., Livasy, Chad, Rugo, Hope S., Esserman, Laura, Park, John W., van ’t Veer, Laura J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479083/
https://www.ncbi.nlm.nih.gov/pubmed/26021444
http://dx.doi.org/10.1186/s13058-015-0582-3