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The Toll-like receptor-4 in human and mouse colonic epithelium is developmentally regulated: a possible role in Necrotizing Enterocolitis

BACKGROUND: Necrotizing enterocolitis (NEC) is an immature intestinal condition resulting in devastating intestinal inflammation due to unknown mechanisms. Evidence has suggested that intestinal maturation attenuates the severity of NEC and TLR4 has been suggested to play a critical role in its path...

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Detalles Bibliográficos
Autores principales: Meng, Di, Zhu, Weishu, Shi, Hai Ning, Lu, Lei, Wijendran, Vasuki, Xu, Winber, Walker, W. Allan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479150/
https://www.ncbi.nlm.nih.gov/pubmed/25521917
http://dx.doi.org/10.1038/pr.2014.207