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Spinal cord stimulation modulates supraspinal centers of the descending antinociceptive system in rats with unilateral spinal nerve injury

BACKGROUND: The descending antinociceptive system (DAS) is thought to play crucial roles in the antinociceptive effect of spinal cord stimulation (SCS), especially through its serotonergic pathway. The nucleus raphe magnus (NRM) in the rostral ventromedial medulla is a major source of serotonin [5-h...

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Detalles Bibliográficos
Autores principales: Tazawa, Toshiharu, Kamiya, Yoshinori, Kobayashi, Ayako, Saeki, Kensuke, Takiguchi, Masahito, Nakahashi, Yusuke, Shinbori, Hironobu, Funakoshi, Kengo, Goto, Takahisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479321/
https://www.ncbi.nlm.nih.gov/pubmed/26104415
http://dx.doi.org/10.1186/s12990-015-0039-9