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Sphingosine-1-phosphate as signaling molecule in the skin: Relevance in atopic dermatitis

Sphingolipids are essential molecules of the mammalian epidermis. Keratinocytes generate and secrete huge amounts of ceramide-precursors to the extracellular domain of the stratum corneum, where they are further metabolized to specific ceramide species. The arrangement of ceramides to well-organized...

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Detalles Bibliográficos
Autores principales: Japtok, Lukasz, Bäumer, Wolfgang, Kleuser, Burkhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Urban & Vogel 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479432/
https://www.ncbi.nlm.nih.gov/pubmed/26120515
http://dx.doi.org/10.1007/s40629-014-0008-2