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Sphingosine-1-phosphate as signaling molecule in the skin: Relevance in atopic dermatitis
Sphingolipids are essential molecules of the mammalian epidermis. Keratinocytes generate and secrete huge amounts of ceramide-precursors to the extracellular domain of the stratum corneum, where they are further metabolized to specific ceramide species. The arrangement of ceramides to well-organized...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Urban & Vogel
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479432/ https://www.ncbi.nlm.nih.gov/pubmed/26120515 http://dx.doi.org/10.1007/s40629-014-0008-2 |