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Simultaneous Inhibition of EGFR/VEGFR and Cyclooxygenase-2 Targets Stemness-Related Pathways in Colorectal Cancer Cells

Despite the demonstrated benefits of anti-EGFR/VEGF targeted therapies in metastatic colorectal cancer (mCRC), many patients initially respond, but then show evidence of disease progression. New therapeutic strategies are needed to make the action of available drugs more efficient. Our study aimed t...

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Detalles Bibliográficos
Autores principales: Valverde, Araceli, Peñarando, Jon, Cañas, Amanda, López-Sánchez, Laura M., Conde, Francisco, Hernández, Vanessa, Peralbo, Esther, López-Pedrera, Chary, de la Haba-Rodríguez, Juan, Aranda, Enrique, Rodríguez-Ariza, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479446/
https://www.ncbi.nlm.nih.gov/pubmed/26107817
http://dx.doi.org/10.1371/journal.pone.0131363