Genome Wide DNA Methylation Profiles Provide Clues to the Origin and Pathogenesis of Germ Cell Tumors

The cell of origin of the five subtypes (I-V) of germ cell tumors (GCTs) are assumed to be germ cells from different maturation stages. This is (potentially) reflected in their methylation status as fetal maturing primordial germ cells are globally demethylated during migration from the yolk sac to...

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Detalles Bibliográficos
Autores principales: Rijlaarsdam, Martin A., Tax, David M. J., Gillis, Ad J. M., Dorssers, Lambert C. J., Koestler, Devin C., de Ridder, Jeroen, Looijenga, Leendert H. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479500/
https://www.ncbi.nlm.nih.gov/pubmed/25859847
http://dx.doi.org/10.1371/journal.pone.0122146

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479500/
https://www.ncbi.nlm.nih.gov/pubmed/25859847
http://dx.doi.org/10.1371/journal.pone.0122146

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