Torin 1 partially corrects vigabatrin-induced mitochondrial increase in mouse

Recent findings in mice with targeted deletion of the GABA-metabolic enzyme succinic semialdehyde dehydrogenase revealed a new role for supraphysiological GABA (4-aminobutyric acid) in the activation of the mechanistic target of rapamycin (mTOR) that results in disruption of endogenous mitophagy. Em...

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Detalles Bibliográficos
Autores principales: Vogel, Kara R, Ainslie, Garrett R, Jansen, Erwin E W, Salomons, Gajja S, Gibson, K Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Brief Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479529/
https://www.ncbi.nlm.nih.gov/pubmed/26125044
http://dx.doi.org/10.1002/acn3.200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479529/
https://www.ncbi.nlm.nih.gov/pubmed/26125044
http://dx.doi.org/10.1002/acn3.200

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