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Leukemogenic rearrangements at the mixed lineage leukemia gene (MLL)—multiple rather than a single mechanism
Despite manifold efforts to achieve reduced-intensity and -toxicity regimens, secondary leukemia has remained the most severe side effect of chemotherapeutic cancer treatment. Rearrangements involving a short telomeric <1 kb region of the mixed lineage leukemia (MLL) gene are the most frequently...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479792/ https://www.ncbi.nlm.nih.gov/pubmed/26161385 http://dx.doi.org/10.3389/fcell.2015.00041 |