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In Vivo Selection of Pan-Drug Resistant Acinetobacter baumannii during Antibiotic Treatment

PURPOSE: Colistin resistance in Acinetobacter baumannii (A. baumannii) is mediated by a complete loss of lipopolysaccharide production via mutations in lpxA, lpxC, and lpxD gene or lipid A modifications via mutations in the pmrA and pmrB genes. However, the exact mechanism of therapy-induced colisti...

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Detalles Bibliográficos
Autores principales: Kim, Yoonjung, Bae, Il Kwon, Jeong, Seok Hoon, Yong, Dongeun, Lee, Kyungwon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Yonsei University College of Medicine 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479859/
https://www.ncbi.nlm.nih.gov/pubmed/26069113
http://dx.doi.org/10.3349/ymj.2015.56.4.928